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Experimental


1. The Road to a Realistic 3D Model for Estimating R and R* Relaxation Versus Gd-DTPA Concentration in Whole Blood and Brain Tumor Vasculature.

van Dorth D, Alafandi A, Soloukey S, Kruizinga P, Venugopal K, Delphin A, Poot DHJ, Christen T, Smits M, de Bresser J, Hernandez-Tamames JA, van Osch MJP
in NMR in biomedicine 2025

2. Genomics yields biological and phenotypic insights into bipolar disorder.

O'Connell KS, Koromina M, van der Veen T, Boltz T, David FS, Yang JMK, Lin KH, Wang X, Coleman JRI, Mitchell BL, McGrouther CC, Rangan AV, Lind PA, Koch E, Harder A, Parker N, Bendl J, Adorjan K, Agerbo E, Albani D, Alemany S, Alliey-Rodriguez N, Als TD, Andlauer TFM, Antoniou A, Ask H, Bass N, Bauer M, Beins EC, Bigdeli TB, Pedersen CB, Boks MP, Børte S, Bosch R, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cabana-Domínguez J, Cairns MJ, Carpiniello B, Casas M, Cervantes P, Chatzinakos C, Chen HC, Clarence T, Clarke TK, Claus I, Coombes B, Corfield EC, Cruceanu C, Cuellar-Barboza A, Czerski PM, Dafnas K, Dale AM, Dalkner N, Degenhardt F, DePaulo JR, Djurovic S, Drange OK, Escott-Price V, Fanous AH, Fellendorf FT, Ferrier IN, Forty L, Frank J, Frei O, Freimer NB, Fullard JF, Garnham J, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha TH, Hahn T, Haraldsson M, Hautzinger M, Havdahl A, Heilbronner U, Hellgren D, Herms S, Hickie IB, Hoffmann P, Holmans PA, Huang MC, Ikeda M, Jamain S, Johnson JS, Jonsson L, Kalman JL, Kamatani Y, Kennedy JL, Kim E, Kim J, Kittel-Schneider S, Knowles JA, Kogevinas M, Kranz TM, Krebs K, Kushner SA, Lavebratt C, Lawrence J, Leber M, Lee HJ, Liao C, Lucae S, Lundberg M, MacIntyre DJ, Maier W, Maihofer AX, Malaspina D, Manchia M, Maratou E, Martinsson L, Mattheisen M, McGregor NW, McInnis MG, McKay JD, Medeiros H, Meyer-Lindenberg A, Millischer V, Morris DW, Moutsatsou P, Mühleisen TW, O'Donovan C, Olsen CM, Panagiotaropoulou G, Papiol S, Pardiñas AF, Park HY, Perry A, Pfennig A, Pisanu C, Potash JB, Quested D, Rapaport MH, Regeer EJ, Rice JP, Rivera M, Schulte EC, Senner F, Shadrin A, Shilling PD, Sigurdsson E, Sindermann L, Sirignano L, Siskind D, Slaney C, Sloofman LG, Smeland OB, Smith DJ, Sobell JL, Soler Artigas M, Stein DJ, Stein F, Su MH, Sung H, Świątkowska B, Terao C, Tesfaye M, Tesli M, Thorgeirsson TE, Thorp JG, Toma C, Tondo L, Tooney PA, Tsai SJ, Tsermpini EE, Vawter MP, Vedder H, Vreeker A, Walters JTR, Winsvold BS, Witt SH, Won HH, Ye R, Young AH, Zandi PP, Zillich L, Adolfsson R, Alda M, Alfredsson L, Backlund L, Baune BT, Bellivier F, Bengesser S, Berrettini WH, Biernacka JM, Boehnke M, Børglum AD, Breen G, Carr VJ, Catts S, Cichon S, Corvin A, Craddock N, Dannlowski U, Dikeos D, Etain B, Ferentinos P, Frye M, Fullerton JM, Gawlik M, Gershon ES, Goes FS, Green MJ, Grigoroiu-Serbanescu M, Hauser J, Henskens FA, Hjerling-Leffler J, Hougaard DM, Hveem K, Iwata N, Jones I, Jones LA, Kahn RS, Kelsoe JR, Kircher T, Kirov G, Kuo PH, Landén M, Leboyer M, Li QS, Lissowska J, Lochner C, Loughland C, Luykx JJ, Martin NG, Mathews CA, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Medland SE, Melle I, Milani L, Mitchell PB, Morken G, Mors O, Mortensen PB, Müller-Myhsok B, Myers RM, Myung W, Neale BM, Nievergelt CM, Nordentoft M, Nöthen MM, Nurnberger JI, O'Donovan MC, Oedegaard KJ, Olsson T, Owen MJ, Paciga SA, Pantelis C, Pato CN, Pato MT, Patrinos GP, Pawlak JM, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribasés M, Rietschel M, Ripke S, Rouleau GA, Roussos P, Saito T, Schall U, Schalling M, Schofield PR, Schulze TG, Scott LJ, Scott RJ, Serretti A, Smoller JW, Squassina A, Stahl EA, Stefansson H, Stefansson K, Stordal E, Streit F, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Waldman ID, Weickert CS, Weickert TW, Werge T, Whiteman DC, Zwart JA, Edenberg HJ, McQuillin A, Forstner AJ, Mullins N, Di Florio A, Ophoff RA, Andreassen OA
in Nature 2025

3. Kilohertz electrical stimulation evokes robust cellular responses like conventional frequencies but distinct population dynamics.

Ravasio CR, Kondabolu K, Zhou S, Lowet E, San Antonio E, Mount RA, Bhogal SK, Han X
in Communications biology 2025

4. How and where Effectively Apply Cerebellum Stimulation: The frequency-dependent Modulation of Cerebellar Output by Transcranial Alternating Current Stimulation.

Romano V, Manto M
in Cerebellum (London, England) 2025

5. A Study on Potential Sources of Perineuronal Net-Associated Sema3A in Cerebellar Nuclei Reveals Toxicity of Non-Invasive AAV-Mediated Cre Expression in the Central Nervous System.

Gimenez GA, Romijn M, van den Herik J, Meijer W, Eggers R, Hobo B, De Zeeuw CI, Canto CB, Verhaagen J, Carulli D
in International journal of molecular sciences 2025

6. Acute aerobic exercise enhances associative learning in regular exercisers but not in non-regular exercisers.

in Frontiers in behavioral neuroscience 2025

7. Encoding of cerebellar dentate neuron activity during visual attention in rhesus macaques.

Flierman NA, Koay SA, van Hoogstraten WS, Ruigrok TJH, Roelfsema P, Badura A, De Zeeuw CI
in eLife 2025

8. Neuronal dynamics of cerebellum and medial prefrontal cortex in adaptive motor timing.

9. Developmental trajectories of visual orienting functions in children born very or extremely preterm.

van Gils MM, Bijlsma A, Vermeulen MJ, Reiss IKM, Joosten KFM, Kooiker MJG, Pel JJM
in Early human development 2025

10. Multiparametric Assays Capture Sex- and Environment-Dependent Modifiers of Behavioral Phenotypes in Autism Mouse Models.

Wahl L, Karim A, Hassett AR, van der Doe M, Dijkhuizen S, Badura A
in Biological psychiatry global open science 2024

11. The modified elevated gap interaction test: a novel paradigm to assess social preference.

12. Classification of Mild Cognitive Impairment and Alzheimer

Koppelmans V, Ruitenberg MFL, Schaefer SY, King JB, Jacobo JM, Silvester BP, Mejia AF, van der Geest J, Hoffman JM, Tasdizen T, Duff K
in Neuro-degenerative diseases 2024

13. The Effect of Nucleo-Olivary Stimulation on Climbing Fiber EPSPs in Purkinje Cells.

Öhman J, Sjölin E, Cundari M, Johansson F, Gilbert M, Boele HJ, Svensson P, Rasmussen A
in Cerebellum (London, England) 2024

14. Temporal evolution of microstructural integrity in cerebellar peduncles in Parkinson's disease: Stage-specific patterns and dopaminergic correlates.

He C, Yang R, Rong S, Zhang P, Chen X, Qi Q, Gao Z, Li Y, Li H, de Leeuw FE, Tuladhar AM, Duering M, Helmich RC, van der Vliet R, Darweesh SKL, Liu Z, Wang L, Cai M, Zhang Y
in NeuroImage. Clinical 2024

15. Outcome measures in Angelman syndrome.

Hagenaar DA, Bindels-de Heus KGCB, van Gils MM, van den Berg L, Ten Hoopen LW, Affourtit P, Pel JJM, Joosten KFM, Hillegers MHJ, Moll HA, de Wit MY, Dieleman GC, Mous SE
in Journal of neurodevelopmental disorders 2024

16. Patient-Specific Vascular Flow Phantom for MRI- and Doppler Ultrasound Imaging.

Soloukey S, Generowicz B, Warnert E, Springeling G, Schouten J, De Zeeuw C, Dirven C, Vincent A, Kruizinga P
in Ultrasound in medicine & biology 2024

17. Eyes on CVI: Eye movements unveil distinct visual search patterns in Cerebral Visual Impairment compared to ADHD, dyslexia, and neurotypical children.

Hokken MJ, Stein N, Pereira RR, Rours IGIJG, Frens MA, van der Steen J, Pel JJM, Kooiker MJG
in Research in developmental disabilities 2024

18. Purkinje cell models: past, present and future

in Frontiers in Computational Neuroscience 2024

19. Genetic investigation of the ubiquitin-protein ligase E3A gene as putative target in Angelman syndrome.

Manoubi W, Mahdouani M, Hmida D, Kdissa A, Rouissi A, Turki I, Gueddiche N, Soyah N, Saad A, Bouwkamp C, Elgersma Y, Mougou-Zerelli S, Gribaa M
in World journal of clinical cases 2024

20. A Reconfigurable Architecture of a Scalable, Ultrafast, Ultrasound, Delay-and-Sum Beamformer.

Vasilis Kypriotis, Georgios Smaragdos, Pieter Kruizinga, Dimitrios Soudris, Christos Strydis
in 2024

21. Metabolomic analysis of dietary-restriction-induced attenuation of sarcopenia in prematurely aging DNA repair-deficient mice.

He Y, Yang W, Huang L, Mever MA, Ramautar R, Harms A, Rijksen Y, Brandt RMC, Barnhoorn S, Smit K, Jaarsma D, Lindenburg P, Hoeijmakers JHJ, Vermeij WP, Hankemeier T
in Journal of cachexia, sarcopenia and muscle 2024

22. Beta-frequency sensory stimulation enhances gait rhythmicity through strengthened coupling between striatal networks and stepping movement.

Sridhar S, Lowet E, Gritton HJ, Freire J, Zhou C, Liang F, Han X
in Nature communications 2024

23. Improved health by combining dietary restriction and promoting muscle growth in DNA repair-deficient progeroid mice.

Vermeij WP, Alyodawi K, van Galen I, von der Heide JL, Birkisdóttir MB, Van't Sant LJ, Ozinga RA, Komninos DSJ, Smit K, Rijksen YMA, Brandt RMC, Barnhoorn S, Jaarsma D, Vaiyapuri S, Ritvos O, Huber TB, Kretz O, Patel K
in Journal of cachexia, sarcopenia and muscle 2024

24. autoMEA: machine learning-based burst detection for multi-electrode array datasets.

Hernandes V, Heuvelmans AM, Gualtieri V, Meijer DH, van Woerden GM, Greplova E
in Frontiers in neuroscience 2024

25. CAMK2; four genes, one syndrome? Delineation of genotype-phenotype correlations.

Cheung JS, van Woerden GM, Veenma DCM
in Current opinion in neurobiology 2024

26. Meeting summary of The NYO3 5th NO-Age/AD meeting and the 1st Norway-UK joint meeting on ageing and dementia: recent progress on the mechanisms and interventional strategies.

Wang HL, Siow R, Schmauck-Medina T, Zhang J, Sandset PM, Filshie C, Lund Ø, Partridge L, Bergersen LH, Juel Rasmussen L, Palikaras K, Sotiropoulos I, Storm-Mathisen J, Rubinsztein DC, Spillantini MG, De Zeeuw CI, Watne LO, Vyhnalek M, Veverova K, Liang KX, Tavernarakis N, Bohr VA, Yokote K, Saarela J, Nilsen H, Gonos ES, Scheibye-Knudsen M, Chen G, Kato H, Selbæk G, Fladby T, Nilsson P, Simonsen A, Aarsland D, Lautrup S, Ottersen OP, Cox LS, Fang EF
in The journals of gerontology. Series A, Biological sciences and medical sciences 2024

27. Effect of ethnic diversity on the saccadic reaction time among healthy Indian and Dutch adults.

Meethal NSK, Mazumdar D, Thepass G, Lemij HG, van der Steen J, Pel JJM, George R
in Scientific reports 2024

28. Different Purkinje cell pathologies cause specific patterns of progressive gait ataxia in mice.

Jaarsma D, Birkisdóttir MB, van Vossen R, Oomen DWGD, Akhiyat O, Vermeij WP, Koekkoek SKE, De Zeeuw CI, Bosman LWJ
in Neurobiology of disease 2024

29. Disynaptic inhibitory cerebellar control over caudal medial accessory olive.

30. Bridging the gap: neurodevelopmental disorder risks in inborn errors of immunity.

Kurup D, FitzPatrick AM, Badura A, Serra I
in Current opinion in allergy and clinical immunology 2024

31. Four-dimensional computational ultrasound imaging of brain hemodynamics.

32. A role for the cerebellum in motor-triggered alleviation of anxiety.

Zhang XY, Wu WX, Shen LP, Ji MJ, Zhao PF, Yu L, Yin J, Xie ST, Xie YY, Zhang YX, Li HZ, Zhang QP, Yan C, Wang F, De Zeeuw CI, Wang JJ, Zhu JN
in Neuron 2024

33. Developmental fine-tuning of medial superior olive neurons mitigates their predisposition to contralateral sound sources.

34. Learning to stand with sensorimotor delays generalizes across directions and from hand to leg effectors.

Rasman BG, Blouin JS, Nasrabadi AM, van Woerkom R, Frens MA, Forbes PA
in Communications biology 2024

35. Keeping track of time: An interaction of mossy fibers and climbing fibers.

36. Population-wide cerebellar growth models of children and adolescents.

Gaiser C, van der Vliet R, de Boer AAA, Donchin O, Berthet P, Devenyi GA, Mallar Chakravarty M, Diedrichsen J, Marquand AF, Frens MA, Muetzel RL
in Nature communications 2024

37. Visual attention and processing function in relation to executive functioning in very preterm-born children aged 3 years: a prospective cohort study.

Bijlsma A, van Gils MM, Beunders VAA, Reiss IKM, Joosten KFM, Pel JJM, Kooiker MJG, Vermeulen MJ
in European journal of pediatrics 2024

38. A Repurposed Drug Selection Pipeline to Identify CNS-Penetrant Drug Candidates for Glioblastoma.

Ntafoulis I, Koolen SLW, van Tellingen O, den Hollander CWJ, Sabel-Goedknegt H, Dijkhuizen S, Haeck J, Reuvers TGA, de Bruijn P, van den Bosch TPP, van Dis V, Gao Z, Dirven CMF, Leenstra S, Lamfers MLM
in Pharmaceuticals (Basel, Switzerland) 2024

39. Lamotrigine for cognitive deficits associated with neurofibromatosis type 1: A phase II randomized placebo-controlled trial.

Ottenhoff MJ, Mous SE, Castricum J, Rietman AB, Oostenbrink R, van der Vaart T, Tulen JHM, Parra A, Ramos FJ, Legius E, Moll HA, Elgersma Y, de Wit MY
in Developmental medicine and child neurology 2024

40. Joining forces to develop individualized antisense oligonucleotides for patients with brain or eye diseases: the example of the Dutch Center for RNA Therapeutics.

Aartsma-Rus A, Collin RWJ, Elgersma Y, Lauffer MC, van Roon-Mom W
in Therapeutic advances in rare disease 2024