lab

Integrative Neurobiology of Psychiatric Disorders

Lab Members

Steven Kushner
Prof.Dr. Steven Kushner (S.A.)
Full Professor
Lab Head
Femke de Vrij
Dr. Femke de Vrij
Assistant Professor
Annelot Esbroeck
Annelot Esbroeck
Postdoctoral Fellow
Sara Hijazi
Sara Hijazi
Postdoctoral Fellow
Jurate Aleknaviciute
Dr. Jurate Aleknaviciute
Postdoctoral Fellow
Bas Lendemeijer
Bas Lendemeijer
Phd Student
Lisa Steenkamp
Lisa Steenkamp
Phd Student
Merel Vries
Merel Vries
Phd Student
Hilde Smeenk
Hilde Smeenk
Phd Student
Rick van der Vliet
Rick van der Vliet
Phd Student
Sakshi Bansal
Sakshi Bansal
Scientific Researcher
Aniek Meesters
Aniek Meesters
Research Technician
Denise Slump
Denise Slump
Research Technician
Mark van der Kroeg
Mark van der Kroeg
Research Technician

Recent Publications

Genetic risk for Alzheimer disease in children: Evidence from early-life IQ and brain white-matter microstructure.

Vinueza-Veloz MF, Martín-Román C, Robalino-Valdivieso MP, White T, Kushner SA, De Zeeuw CI
in Genes, brain, and behavior 2020

Synthetic Polymers Provide a Robust Substrate for Functional Neuron Culture.

Zhang Y, Venkateswaran S, Higuera GA, Nath S, Shpak G, Matray J, Fratila-Apachitei LE, Zadpoor AA, Kushner SA, Bradley M, De Zeeuw CI
in Advanced healthcare materials 2020

Second-tier trio exome sequencing after negative solo clinical exome sequencing: an efficient strategy to increase diagnostic yield and decipher molecular bases in undiagnosed developmental disorders.

Tran Mau-Them F, Moutton S, Racine C, Vitobello A, Bruel AL, Nambot S, Kushner SA, de Vrij FMS, Lehalle D, Jean-Marçais N, Lecoquierre F, Delanne J, Thevenon J, Poe C, Jouan T, Chevarin M, Geneviève D, Willems M, Coubes C, Houcinat N, Masurel-Paulet A, Mosca-Boidron AL, Tisserant E, Callier P, Sorlin A, Duffourd Y, Faivre L, Philippe C, Thauvin-Robinet C
in Human genetics 2020

Long-Term Outcomes of Postpartum Psychosis: A Systematic Review and Meta-Analysis.

Gilden J, Kamperman AM, Munk-Olsen T, Hoogendijk WJG, Kushner SA, Bergink V
in The Journal of clinical psychiatry 2020

Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome.

A functional variant in the miR-142 promoter modulating its expression and conferring risk of Alzheimer disease.

Ghanbari M, Munshi ST, Ma B, Lendemeijer B, Bansal S, Adams HH, Wang W, Goth K, Slump DE, van den Hout MCGN, van IJcken WFJ, Bellusci S, Pan Q, Erkeland SJ, de Vrij FMS, Kushner SA, Ikram MA
in Human mutation 2019

Engram-specific transcriptome profiling of contextual memory consolidation.

Rao-Ruiz P, Couey JJ, Marcelo IM, Bouwkamp CG, Slump DE, Matos MR, van der Loo RJ, Martins GJ, van den Hout M, van IJcken WF, Costa RM, van den Oever MC, Kushner SA
in Nature communications 2019

Intranasal administration of oxytocin decreases task-related aggressive responses in healthy young males.

Berends YR, Tulen JHM, Wierdsma AI, van Pelt J, Feldman R, Zagoory-Sharon O, de Rijke YB, Kushner SA, van Marle HJC
in Psychoneuroendocrinology 2019

Oxytocin, vasopressin and trust: Associations with aggressive behavior in healthy young males.

Berends YR, Tulen JHM, Wierdsma AI, van Pelt J, Kushner SA, van Marle HJC
in Physiology & behavior 2019

Netrin-G2 dysfunction causes a Rett-like phenotype with areflexia

Heimer G, Van Woerden GM, Barel O, Marek-Yagel D, Kol N, Munting JB, Borghei M, Atawneh OM, Nissenkom A, Rechavi G, Anikster Y, Elgersma Y, Kushner SA, Ben Zeev B
in Hum Mutat 2019

Novel genetic loci affecting facial shape variation in humans.

Xiong Z, Dankova G, Howe LJ, Lee MK, Hysi PG, de Jong MA, Zhu G, Adhikari K, Li D, Li Y, Pan B, Feingold E, Marazita ML, Shaffer JR, McAloney K, Xu SH, Jin L, Wang S, de Vrij FM, Lendemeijer B, Richmond S, Zhurov A, Lewis S, Sharp GC, Paternoster L, Thompson H, Gonzalez-Jose R, Bortolini MC, Canizales-Quinteros S, Gallo C, Poletti G, Bedoya G, Rothhammer F, Uitterlinden AG, Ikram MA, Wolvius E, Kushner SA, Nijsten TE, Palstra RT, Boehringer S, Medland SE, Tang K, Ruiz-Linares A, Martin NG, Spector TD, Stergiakouli E, Weinberg SM, Liu F, Kayser M
in eLife 2019

Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex.

Stedehouder J, Brizee D, Slotman JA, Pascual-Garcia M, Leyrer ML, Bouwen BL, Dirven CM, Gao Z, Berson DM, Houtsmuller AB, Kushner SA
in eLife 2019

TMS motor mapping: Comparing the absolute reliability of digital reconstruction methods to the golden standard.

Jonker ZD, van der Vliet R, Hauwert CM, Gaiser C, Tulen JHM, van der Geest JN, Donchin O, Ribbers GM, Frens MA, Selles RW
in Brain Stimul. 2019

Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia.

de Vrij FM, Bouwkamp CG, Gunhanlar N, Shpak G, Lendemeijer B, Baghdadi M, Gopalakrishna S, Ghazvini M, Li TM, Quadri M, Olgiati S, Breedveld GJ, Coesmans M, Mientjes E, de Wit T, Verheijen FW, Beverloo HB, Cohen D, Kok RM, Bakker PR, Nijburg A, Spijker AT, Haffmans PMJ, Hoencamp E, Bergink V, Vorstman JA, Wu T, Olde Loohuis LM, Amin N, Langen CD, Hofman A, Hoogendijk WJ, van Duijn CM, Ikram MA, Vernooij MW, Tiemeier H, Uitterlinden AG, Elgersma Y, Distel B, Gribnau J, White T, Bonifati V, Kushner SA
in Molecular psychiatry 2018

The Zinc Transporter SLC39A7 (ZIP7) Is Essential for Regulation of Cytosolic Zinc Levels.

Woodruff G, Bouwkamp CG, de Vrij FM, Lovenberg T, Bonaventure P, Kushner SA, Harrington AW
in Molecular pharmacology 2018
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Vacancies

There are currently no vacancies on our lab.

Cross-section of mouse prefrontal cortex with bilateral symmetric viral labeling (yellow/red) and myelination (green)

Cross-section of mouse prefrontal cortex with bilateral symmetric viral labeling (yellow/red) and myelination (green)