Vacancies

Mutations in the PTEN and PI3K genes have been shown to increase the risks for ASD. However, the function of these proteins in the brain and their role in ASD are largely unknown. The PhD student on this project will: characterize the interactions between PTEN and PI3K mutations and the mTOR pathway in neurons at the m...

Over the last decade, an increasing amount of effort has been spent on constructing and, then, simulating powerful brain models that can greatly help in unraveling the mysteries of the human brain (see for instance the EU flagship Human Brain Project). Whereas these models are powerful and constantly come closer to...

One of the most difficult challenges in Computational Neuroscience is to find adequate mathematical tools to simulate detailed biophysical models of neuronal networks accurately and fast. The computational demands of such simulations are huge and more so when we consider the problem size: thousands to millions of neuro...

One of the most difficult challenges in Computational Neuroscience is to find adequate mathematical tools to simulate detailed biophysical models of neuronal networks accurately and fast. The computational demands of such simulations are huge and more so when we consider the problem size: thousands to millions of neuro...

Bij oorsuizen (tinnitus) hoor je geluiden die er niet zijn. Dit is een frequent voorkomende, meestal chronische aandoening, waarvan de oorzaak nog niet goed bekend is, waarvoor geen objectieve test bestaat en waarvoor de behandelingsmogelijkheden beperkt zijn (Bauer 2018, http://doi.org/10.1056/NEJMcp1506631). In dit m...