lab

Title follows Henk-Jan Boele

Lab Head: Henk Jan-Boele

Lab Description


Lab Members

Henk Jan Boele
Dr. Henk Jan Boele (H.J.)
Assistant Professor
Lab Head
Kayleigh Gultig
Kayleigh Gultig
Phd Student
Ting Fang Soong
Ting Fang Soong
Master Student
Florine Brinkman
Florine Brinkman
Master Student
Gillian de Zwart
Gillian de Zwart
Master Student
Sara Milosevska
Sara Milosevska
Master Student
Katja Podvinsek
Katja Podvinsek
Research Assistant

Recent Publications

Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors.

Beekhof GC, Osório C, White JJ, van Zoomeren S, van der Stok H, Xiong B, Nettersheim IH, Mak WA, Runge M, Fiocchi FR, Boele HJ, Hoebeek FE, Schonewille M
in eLife 2021
DOI: 10.7554/eLife.63668

Young Domestic Pigs Can Perform Pavlovian Eyeblink Conditioning.

Boele HJ, Joung S, Fil JE, Mudd AT, Fleming SA, Koekkoek SKE, Dilger RN
in Frontiers in behavioral neuroscience 2021
DOI: 10.3389/fnbeh.2021.690019

Homologous organization of cerebellar pathways to sensory, motor, and associative forebrain.

Pisano TJ, Dhanerawala ZM, Kislin M, Bakshinskaya D, Engel EA, Hansen EJ, Hoag AT, Lee J, de Oude NL, Venkataraju KU, Verpeut JL, Hoebeek FE, Richardson BD, Boele HJ, Wang SS
in Cell reports 2021
DOI: 10.1016/j.celrep.2021.109721

AMPAR Auxiliary Protein SHISA6 Facilitates Purkinje Cell Synaptic Excitability and Procedural Memory Formation.

Peter S, Urbanus BHA, Klaassen RV, Wu B, Boele HJ, Azizi S, Slotman JA, Houtsmuller AB, Schonewille M, Hoebeek FE, Spijker S, Smit AB, De Zeeuw CI
in Cell reports 2020
DOI: 10.1016/j.celrep.2020.03.079

Cerebellar plasticity and associative memories are controlled by perineuronal nets.

Carulli D, Broersen R, de Winter F, Muir EM, Mešković M, de Waal M, de Vries S, Boele HJ, Canto CB, De Zeeuw CI, Verhaagen J
in Proceedings of the National Academy of Sciences of the United States of America 2020
DOI: 10.1073/pnas.1916163117

SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning-specific memory traces.

Grasselli G, Boele HJ, Titley HK, Bradford N, van Beers L, Jay L, Beekhof GC, Busch SE, De Zeeuw CI, Schonewille M, Hansel C
in PLoS biology 2020
DOI: 10.1371/journal.pbio.3000596

Pavlovian eyeblink conditioning is severely impaired in tottering mice.

de Oude NL, Hoebeek FE, Ten Brinke MM, de Zeeuw CI, Boele HJ
in Journal of neurophysiology 2020
DOI: 10.1152/jn.00578.2020

TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells.

Wu B, Blot FG, Wong AB, Osório C, Adolfs Y, Pasterkamp RJ, Hartmann J, Becker EB, Boele HJ, De Zeeuw CI, Schonewille M
in eLife 2019
DOI: 10.7554/eLife.45590

Cerebellar learning properties are modulated by the CRF receptor in granular cells.

Ezra-Nevo G, Prestori F, Locatelli F, Soda T, Ten Brinke MM, Engel M, Boele HJ, Botta L, Leshkowitz D, Ramot A, Tsoory M, Biton IE, Deussing J, D'Angelo E, De Zeeuw CI, Chen A
in The Journal of neuroscience : the official journal of the Society for Neuroscience 2018
DOI: 10.1523/JNEUROSCI.3106-15.2018

Impact of parallel fiber to Purkinje cell long-term depression is unmasked in absence of inhibitory input.

Boele HJ, Peter S, Ten Brinke MM, Verdonschot L, IJpelaar ACH, Rizopoulos D, Gao Z, Koekkoek SKE, De Zeeuw CI
in Science advances 2018
DOI: 10.1126/sciadv.aas9426

High Frequency Functional Ultrasound in Mice

S.K.E. Koekkoek , S. Soloukey Tbalvandany, B.S. Generowicz, W.S. van Hoogstraten, N.L. de Oude, H.J. Boele, C. Strydis, G. Leus, J.G. Bosch, A.F.W. van der Steen, C. I. de Zeeuw, and P. Kruizinga
in IEEE International Ultrasonics Symposium (IUS) 2018
DOI: 10.1109/ULTSYM.2018.8579865

Dynamic modulation of activity in cerebellar nuclei neurons during pavlovian eyeblink conditioning in mice.

Ten Brinke MM, Heiney SA, Wang X, Proietti-Onori M, Boele HJ, Bakermans J, Medina JF, Gao Z, De Zeeuw CI
in eLife 2017
DOI: 10.7554/eLife.28132

Performance in eyeblink conditioning is age and sex dependent.

Löwgren K, Bååth R, Rasmussen A, Boele HJ, Koekkoek SKE, De Zeeuw CI, Hesslow G
in PloS one 2017
DOI: 10.1371/journal.pone.0177849

Modulation of 7 T fMRI Signal in the Cerebellar Cortex and Nuclei During Acquisition, Extinction, and Reacquisition of Conditioned Eyeblink Responses.

Ernst TM, Thürling M, Müller S, Kahl F, Maderwald S, Schlamann M, Boele HJ, Koekkoek SKE, Diedrichsen J, De Zeeuw CI, Ladd ME, Timmann D
in Human brain mapping 2017
DOI: 10.1002/hbm.23641

Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice.

Peter S, Ten Brinke MM, Stedehouder J, Reinelt CM, Wu B, Zhou H, Zhou K, Boele HJ, Kushner SA, Lee MG, Schmeisser MJ, Boeckers TM, Schonewille M, Hoebeek FE, De Zeeuw CI
in Nature communications 2016
DOI: 10.1038/ncomms12627
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Vacancies

There are currently no vacancies on our lab.