Laurens Bosman

contact

  • l.bosman@erasmusmc.nl
  • +31 010 7043358
  • Room: Ee-1208
  • Dr. Molewaterplein 40, Faculty Building, Rotterdam, The Netherlands

Social Media

Dr. Laurens Bosman (L.W.J.)

Biography

Laurens Bosman studied biology / biophysics at Leiden University and obtained his PhD in membrane physiology at the Vrije Universiteit Amsterdam. As post-doctoral fellow, he worked together with Arthur Konnerth at the Ludwig-Maximilians-Universität and the Techische Universität München in Germany. Currently, he works as assistant professor at the Department of Neuroscience of the Erasmus MC, chaired by Chris De Zeeuw. In his research, he focuses on how the cerebellum cooperates with other brain regions to adjust behavior in response to sensory feedback in health and disease.

Research Interests

  1. Sensorimotor integration in the cerebro-cerebellar circuits
  2. Rodent whisker system
  3. Neural control of walking
  4. Neural control of respiration
  5. Spinocerebellar ataxia
  6. Climbing fiber development
  7. Animal ethics

Education

MSc in Biology (cum laude), Rijksuniversiteit Leiden, Leiden, The Netherlands; PhD in Earth and Life Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands (promoter: prof. Arjen Brussaard)

Publications

1. Different Purkinje cell pathologies cause specific patterns of progressive gait ataxia in mice.

Jaarsma D, Birkisdóttir MB, van Vossen R, Oomen DWGD, Akhiyat O, Vermeij WP, Koekkoek SKE, De Zeeuw CI, Bosman LWJ
in Neurobiology of disease 2024
DOI: 10.1016/j.nbd.2024.106422

2. Correction to: A Systematic Review of Direct Outputs from the Cerebellum to the Brainstem and Diencephalon in Mammals.

Novello M, Bosman LWJ, De Zeeuw CI
in Cerebellum (London, England) 2023
DOI: 10.1007/s12311-023-01566-w

3. The integrated brain network that controls respiration.

Krohn F, Novello M, van der Giessen RS, De Zeeuw CI, Pel JJM, Bosman LWJ
in eLife 2023
DOI: 10.7554/eLife.83654

4. A Systematic Review of Direct Outputs from the Cerebellum to the Brainstem and Diencephalon in Mammals.

Novello M, Bosman LWJ, De Zeeuw CI
in Cerebellum (London, England) 2022
DOI: 10.1007/s12311-022-01499-w

5. WhiskEras 2.0 - Fast and Accurate Whisker Tracking in Rodents.

Petros Arvanitis, Jan-Harm L. F. Betting, Laurens W. J. Bosman, Zaid Al-Ars, Christos Strydis
in 2021
DOI: 10.1007/978-3-031-04580-6_14

6. Cerebellar Purkinje cells can differentially modulate coherence between sensory and motor cortex depending on region and behavior.

Lindeman S, Hong S, Kros L, Mejias JF, Romano V, Oostenveld R, Negrello M, Bosman LWJ, De Zeeuw CI
in Proceedings of the National Academy of Sciences of the United States of America 2021
DOI: 10.1073/pnas.2015292118

7. Inducible expression of human C9ORF72 36x G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice

F.W. Riemslagh, E.C. van der Toorn, R.F.M. Verhagen, A. Maas, L.W.J. Bosman, R.K. Hukema, R. Willemsen
in Disease Models & Mechanisms 2021
DOI: https://dmm.biologists.org/content/early/2021/01/10/dmm.044842

8. Region-specific preservation of Purkinje cell morphology and motor behavior in the ATXN1[82Q] mouse model of spinocerebellar ataxia 1.

White JJ, Bosman LWJ, Blot FGC, Osório C, Kuppens BW, Krijnen WHJJ, Andriessen C, De Zeeuw CI, Jaarsma D, Schonewille M
in Brain pathology (Zurich, Switzerland) 2021
DOI: 10.1111/bpa.12946

9. Purkinje cells translate subjective salience into readiness to act and choice performance.

Bina L, Romano V, Hoogland TM, Bosman LWJ, De Zeeuw CI
in Cell reports 2021
DOI: 10.1016/j.celrep.2021.110116

10. Stairway to Abstraction - an Iterative Algorithm for Whisker Detection in Video Frames.

Jan-Harm L. F. Betting, Vincenzo Romano, Laurens W. J. Bosman, Zaid Al-Ars, Chris I. De Zeeuw, Christos Strydis
in 2020 IEEE 11th Latin American Symposium on Circuits Systems (LASCAS) 2020
DOI: 10.1109/LASCAS45839.2020.9068992
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