lab

Neurodynamics of Computation

Lab Head: Mario-Negrello

Lab Description


Lab Members

Mario Negrello
Dr. Mario Negrello (MN)
Associate Professor
Lab Head

Recent Publications

Homeostatic bidirectional plasticity in upbound and downbound micromodules in a model of the olivocerebellar loop.

Fernández Santoro EM, Landsmeer LPL, Hamdioui S, Strydis C, De Zeeuw CI, Badura A, Negrello M
in PLoS computational biology 2025
DOI: 10.1371/journal.pcbi.1013609

Purkinje cell models: past, present and future

Fernández Santoro Elías Mateo , Karim Arun , Warnaar Pascal , De Zeeuw Chris I. , Badura Aleksandra , Negrello Mario
in Frontiers in Computational Neuroscience 2024
DOI: 10.3389/fncom.2024.1426653

How inhibitory and excitatory inputs gate output of the inferior olive.

Loyola S, Hoogland TM, Hoedemaker H, Romano V, Negrello M, De Zeeuw CI
in eLife 2023
DOI: 10.7554/eLife.83239

EDEN: A High-Performance, General-Purpose, NeuroML-Based Neural Simulator.

Panagiotou S, Sidiropoulos H, Soudris D, Negrello M, Strydis C
in Frontiers in neuroinformatics 2022
DOI: 10.3389/fninf.2022.724336

Cerebellar Purkinje cells can differentially modulate coherence between sensory and motor cortex depending on region and behavior.

Lindeman S, Hong S, Kros L, Mejias JF, Romano V, Oostenveld R, Negrello M, Bosman LWJ, De Zeeuw CI
in Proceedings of the National Academy of Sciences of the United States of America 2021
DOI: 10.1073/pnas.2015292118

Synthesis-Free, Flexible and Fast Hardware Library for Biophysically Plausible Neurosimulations - POSTER

Rene Miedema, Georgios Smaragdos, Mario Negrello, Zaid Al-Ars, Matthias Möller, and Christos Strydis
in FPGA '20: The 2020 ACM/SIGDA International Symposium on Field-Programmable Gate Arrays 2020
DOI: 10.1145/3373087.3375374

NINscope, a versatile miniscope for multi-region circuit investigations.

de Groot A, van den Boom BJ, van Genderen RM, Coppens J, van Veldhuijzen J, Bos J, Hoedemaker H, Negrello M, Willuhn I, De Zeeuw CI, Hoogland TM
in eLife 2020
DOI: 10.7554/eLife.49987

flexHH: A Flexible Hardware Library for Hodgkin-Huxley-Based Neural Simulations

Miedema R, Smaragdos G, Negrello M, Al-Ars Z, Möller M, Strydis C
in IEEE Access 2020
DOI: https://dx.doi.org/10.1109/ACCESS.2020.3007019

Functional Convergence of Autonomic and Sensorimotor Processing in the Lateral Cerebellum.

Romano V, Reddington AL, Cazzanelli S, Mazza R, Ma Y, Strydis C, Negrello M, Bosman LWJ, De Zeeuw CI
in Cell reports 2020
DOI: 10.1016/j.celrep.2020.107867

Multinode implementation of an extended Hodgkin-Huxley simulator.

George Chatzikonstantis, Harry Sidiropoulos, Christos Strydis, Mario Negrello, Georgios Smaragdos, Chris I. De Zeeuw, Dimitrios Soudris
in Neurocomputing 2019
DOI: 10.1016/J.NEUCOM.2018.10.062

Glissades Are Altered by Lesions to the Oculomotor Vermis but Not by Saccadic Adaptation

Flierman N.A., Ignashchenkova A., Negrello M., Their P., De Zeeuw C.I., Badura A.
in Frontiers in Behavioral Neuroscience 2019
DOI: 10.3389/fnbeh.2019.00194

Quasiperiodic rhythms of the inferior olive.

Negrello M, Warnaar P, Romano V, Owens CB, Lindeman S, Iavarone E, Spanke JK, Bosman LWJ, De Zeeuw CI
in PLoS computational biology 2019
DOI: 10.1371/journal.pcbi.1006475

Variability and directionality of inferior olive neuron dendrites revealed by detailed 3D characterization of an extensive morphological library.

Vrieler N, Loyola S, Yarden-Rabinowitz Y, Hoogendorp J, Medvedev N, Hoogland TM, De Zeeuw CI, De Schutter E, Yarom Y, Negrello M, Torben-Nielsen B, Uusisaari MY
in Brain structure & function 2019
DOI: 10.1007/s00429-019-01859-z

Neurons of the inferior olive respond to broad classes of sensory input while subject to homeostatic control.

Ju C, Bosman LWJ, Hoogland TM, Velauthapillai A, Murugesan P, Warnaar P, van Genderen RM, Negrello M, De Zeeuw CI
in The Journal of physiology 2019
DOI: 10.1113/JP277413

Correction - Spatiotemporal network coding of physiological mossy fiber inputs by the cerebellar granular layer.

Shyam Kumar Sudhakar, Sungho Hong, Ivan Raikov, Rodrigo Publio, Claus Lang, Thomas G. Close, Daqing Guo, Mario Negrello, Erik De Schutter
in PLoS Computational Biology 2019
DOI: 10.1371/JOURNAL.PCBI.1007472
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Vacancies

There are currently no vacancies on our lab.