Martijn  Sierksma


Martijn Sierksma (MC)


Martijn C. Sierksma is a postdoctoral associate of the Department of Neuroscience at Erasmus MC Rotterdam. He received his PhD from Erasmus University Rotterdam in 2018 for his work on neural activity during the formation of the calyx of Held synapse under the supervision of Prof. J. G. G. Borst. His postdoctoral work with Dr X. Nicol at the Vision Institute in Paris has focused on developmental interactions between adjacent retinal ganglion cells that inform the development of the retinogeniculate projection. He collaborated with Dr. R. Brette on the action potential backpropagation and the axial current at spike initiation for developing retinal ganglion cells. He is currently working on synapse development within the superior olivary complex that enable sound localization.


1. Developmental fine-tuning of medial superior olive neurons mitigates their predisposition to contralateral sound sources.

2. Electrical match between initial segment and somatodendritic compartment for action potential backpropagation in retinal ganglion cells.

Goethals S, Sierksma MC, Nicol X, Reaux-Le Goazigo A, Brette R
in Journal of neurophysiology 2021

3. Using ephaptic coupling to estimate the synaptic cleft resistivity of the calyx of Held synapse.

in PLoS computational biology 2021

4. Structure-function relation of the developing calyx of Held synapse in vivo.

Sierksma MC, Slotman JA, Houtsmuller AB, Borst JGG
in The Journal of physiology 2020

5. Resistance to action potential depression of a rat axon terminal in vivo.

in Proceedings of the National Academy of Sciences of the United States of America 2017

6. In vivo matching of postsynaptic excitability with spontaneous synaptic inputs during formation of the rat calyx of Held synapse.

Sierksma MC, Tedja MS, Borst JG
in The Journal of physiology 2016
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