lab

The development of cerebellar function and its role in sensorimotor integration

Lab Members

Martijn Schonewille
Dr. Martijn Schonewille (M)
Associate Professor
Lab Head
Friederike Stephani
Dr. Friederike Stephani
Postdoctoral Fellow
Catarina Osorio
Dr. Catarina Osorio
Postdoctoral Fellow
Joshua White
Dr. Joshua White
Postdoctoral Fellow
Gerco Beekhof
Mr. Gerco Beekhof
Phd Student
Francois Blot
Francois Blot
Phd Student
Bin Wu
Bin Wu
Phd Student
Bilian Xiong
Bilian Xiong
Master Student
Laura Post
Laura Post
Research Technician

Recent Publications

TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells.

Wu B, Blot FG, Wong AB, Osório C, Adolfs Y, Pasterkamp RJ, Hartmann J, Becker EB, Boele HJ, De Zeeuw CI, Schonewille M
in eLife 2019

The basal interstitial nucleus (BIN) of the cerebellum provides diffuse ascending inhibitory input to the floccular granule cell layer.

Jaarsma D, Blot FGC, Wu B, Venkatesan S, Voogd J, Meijer D, Ruigrok TJH, Gao Z, Schonewille M, De Zeeuw CI
in The Journal of comparative neurology 2018

Correction to: Cerebellar Modules and Their Role as Operational Cerebellar Processing Units: A Consensus paper.

Apps R, Hawkes R, Aoki S, Bengtsson F, Brown AM, Chen G, Ebner TJ, Isope P, Jörntell H, Lackey EP, Lawrenson C, Lumb B, Schonewille M, Sillitoe RV, Spaeth L, Sugihara I, Valera A, Voogd J, Wylie DR, Ruigrok TJH
in Cerebellum (London, England) 2018

Cerebellar Modules and Their Role as Operational Cerebellar Processing Units.

Apps R, Hawkes R, Aoki S, Bengtsson F, Brown AM, Chen G, Ebner TJ, Isope P, Jörntell H, Lackey EP, Lawrenson C, Lumb B, Schonewille M, Sillitoe RV, Spaeth L, Sugihara I, Valera A, Voogd J, Wylie DR, Ruigrok TJH
in Cerebellum (London, England) 2018

Impairment of Long-Term Plasticity of Cerebellar Purkinje Cells Eliminates the Effect of Anodal Direct Current Stimulation on Vestibulo-Ocular Reflex Habituation.

Das S, Spoor M, Sibindi TM, Holland P, Schonewille M, De Zeeuw CI, Frens MA, Donchin O
in Frontiers in neuroscience 2017

Mechanisms underlying vestibulo-cerebellar motor learning in mice depend on movement direction

in Journal of Physiology 2017

Modeled changes of cerebellar activity in mutant mice are predictive of their learning impairments.

in Scientific reports 2016

Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice.

Peter S, Ten Brinke MM, Stedehouder J, Reinelt CM, Wu B, Zhou H, Zhou K, Boele HJ, Kushner SA, Lee MG, Schmeisser MJ, Boeckers TM, Schonewille M, Hoebeek FE, De Zeeuw CI
in Nature communications 2016

SLC26A11 (KBAT) in Purkinje Cells Is Critical for Inhibitory Transmission and Contributes to Locomotor Coordination.

Rahmati N, Vinueza Veloz MF, Xu J, Barone S, Rodolfo Ben Hamida N, Schonewille M, Hoebeek FE, Soleimani M, De Zeeuw CI
in eNeuro 2016

Reversibility of neuropathology and motor deficits in an inducible mouse model for FXTAS.

Hukema RK, Buijsen RA, Schonewille M, Raske C, Severijnen LA, Nieuwenhuizen-Bakker I, Verhagen RF, van Dessel L, Maas A, Charlet-Berguerand N, De Zeeuw CI, Hagerman PJ, Berman RF, Willemsen R
in Human molecular genetics 2015

Differential Purkinje cell simple spike activity and pausing behavior related to cerebellar modules.

Zhou H, Voges K, Lin Z, Ju C, Schonewille M
in Journal of neurophysiology 2015

Polarity-dependent effects of trans-cranial direct current stimulation (tDCS) in cerebellar learning depends on the state of neuronal network

Das, S., Holland, P., Schonewille, M., de Zeeuw, C., Frens, M. A. and Donchin, O.
in BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation 2014

Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis

Sepulveda-Falla, D., Barrera-Ocampo, A., Hagel, C., Korwitz, A., Vinueza-Veloz, M. F., Zhou, K., Schonewille, M., Zhou, H., Velazquez-Perez, L., Rodriguez-Labrada, R., Villegas, A., Ferrer, I., Lopera, F., Langer, T., De Zeeuw, C. I. and Glatzel, M.
in Journal of Clinical Investigation 2014

Cerebellar modules operate at different frequencies

Zhou, H., Lin, Z., Voges, K., Ju, C., Gao, Z., Bosman, L. W. J., Ruigrok, T. J., Hoebeek, F. E., De Zeeuw, C. I. and Schonewille, M
in eLife 2014

Temporal and region-specific requirements of αCaMKII in spatial and contextual learning.

Achterberg KG, Buitendijk GH, Kool M, Goorden SM, Post L, Slump DE, Silva AJ, van Woerden GM, Kushner SA, Elgersma Y
in Journal of Neuroscience 2014
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Vacancies

There are currently no vacancies on our lab.