lab

Neural networks underlying behavioral flexibility

Lab Members

Aleksandra Badura
Dr. Aleksandra Badura
Associate Professor
Lab Head
Ines Serra
Dr. Ines Serra
Assistant Professor
Nina Meesters
Nina Meesters
Phd Student
Devika Kurup
Devika Kurup
Phd Student
Lucas Wahl
Lucas Wahl
Phd Student
Mick Koning de
Mick Koning de
Master Student
Ilse Klinkhamer
Ilse Klinkhamer
Master Student
Max van der Doe
Max van der Doe
Master Student
Thomas Jacobs
Thomas Jacobs
Research Technician
Fabian Kaiser
Dr. Fabian Kaiser
Research Fellow
Stephanie Dijkhuizen
Stephanie Dijkhuizen
Project Manager
Cody Knetemann
Cody Knetemann
Bachelor Student
Emma Boer den
Emma Boer den
Bachelor Student

Selected Publications

Delay eyeblink conditioning performance and brain-wide c-Fos expression in male and female mice.

Cognitive-Affective Functions of the Cerebellum.

Rudolph S, Badura A, Lutzu S, Pathak SS, Thieme A, Verpeut JL, Wagner MJ, Yang YM, Fioravante D
in The Journal of neuroscience : the official journal of the Society for Neuroscience 2023

A novel automated approach for improving standardization of the marble burying test enables quantification of burying bouts and activity characteristics

Lucas Wahl, A. Mattijs Punt, Tara Arbab, Ingo Willuhn, Ype Elgersma, Aleksandra Badura
in eNeuro 2022

Tsc1 Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum

Ines Serra, Ana Stravs, Catarina Osório, Maria Roa Oyaga, Martijn Schonewille, Christian Tudorache, and Aleksandra Badura
in Front Mol Neurosci. 2022

Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder.

Kaiser FMP, Gruenbacher S, Oyaga MR, Nio E, Jaritz M, Sun Q, van der Zwaag W, Kreidl E, Zopf LM, Dalm VASH, Pel J, Gaiser C, van der Vliet R, Wahl L, Rietman A, Hill L, Leca I, Driessen G, Laffeber C, Brooks A, Katsikis PD, Lebbink JHG, Tachibana K, van der Burg M, De Zeeuw CI, Badura A, Busslinger M
in The Journal of experimental medicine 2022

Recent Publications

Four-dimensional computational ultrasound imaging of brain hemodynamics.

Delay eyeblink conditioning performance and brain-wide c-Fos expression in male and female mice.

Modeling and Inference of Sparse Neural Dynamic Functional Connectivity Networks Underlying Functional Ultrasound Data.

Ruben Wijnands, Justin Dauwels, Ines Serra, Pieter Kruizinga, Aleksandra Badura, Borbála Hunyadi
in 2023

Cognitive-Affective Functions of the Cerebellum.

Rudolph S, Badura A, Lutzu S, Pathak SS, Thieme A, Verpeut JL, Wagner MJ, Yang YM, Fioravante D
in The Journal of neuroscience : the official journal of the Society for Neuroscience 2023

Whisker kinematics in the cerebellum.

in The Journal of physiology 2023

Measuring Cerebellar Processing and Sensorimotor Functions in Non-Human Primates

Nico A. Flierman, Eric Avila, Chris I. De Zeeuw, Aleksandra Badura
in 2022

A novel automated approach for improving standardization of the marble burying test enables quantification of burying bouts and activity characteristics

Lucas Wahl, A. Mattijs Punt, Tara Arbab, Ingo Willuhn, Ype Elgersma, Aleksandra Badura
in eNeuro 2022

Purkinje Cell Activity in the Medial and Lateral Cerebellum During Suppression of Voluntary Eye Movements in Rhesus Macaques.

Avila E, Flierman NA, Holland PJ, Roelfsema PR, Frens MA, Badura A, De Zeeuw CI
in Frontiers in cellular neuroscience 2022

Tsc1 Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum

Ines Serra, Ana Stravs, Catarina Osório, Maria Roa Oyaga, Martijn Schonewille, Christian Tudorache, and Aleksandra Badura
in Front Mol Neurosci. 2022

Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder.

Kaiser FMP, Gruenbacher S, Oyaga MR, Nio E, Jaritz M, Sun Q, van der Zwaag W, Kreidl E, Zopf LM, Dalm VASH, Pel J, Gaiser C, van der Vliet R, Wahl L, Rietman A, Hill L, Leca I, Driessen G, Laffeber C, Brooks A, Katsikis PD, Lebbink JHG, Tachibana K, van der Burg M, De Zeeuw CI, Badura A, Busslinger M
in The Journal of experimental medicine 2022

Olivocerebellar control of movement symmetry.

Romano V, Zhai P, van der Horst A, Mazza R, Jacobs T, Bauer S, Wang X, White JJ, De Zeeuw CI
in Current biology : CB 2022

Purkinje Cell Activity Resonation Generates Rhythmic Behaviors at the Preferred Frequency of 8 Hz.

Activated PI3Kδ syndrome, an immunodeficiency disorder, leads to sensorimotor deficits recapitulated in a murine model.

Ines Serra, Olivia R. Manusama, Fabian.M.P. Kaiser, Izi Izumi Floriano, Lucas Wahl, Christian van der Zalm, Hanna IJspeert, P. Martin van Hagen, Nico J.M. van Beveren, Sandra M. Arend, Klaus Okkenhaug, Johan J.M. Pel, Virgil A.S.H. Dalm, Aleksandra Badura
in Brain, Behavior, & Immunity - Health 2021

Glissades Are Altered by Lesions to the Oculomotor Vermis but Not by Saccadic Adaptation

Flierman N.A., Ignashchenkova A., Negrello M., Their P., De Zeeuw C.I., Badura A.
in Frontiers in Behavioral Neuroscience 2019

Normal cognitive and social development require posterior cerebellar activity

Badura A., Verpeut J.L., Metzger J.W, Pereira T.D, Pisano T.J., Deverett B., Bakshinskaya D.E., Wang S.S.-H
in eLife 2018
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Alumni

# Name Job Description Current Position
1 Arun Karim Master student PhD student at Donders Institute
2 Nynke Hettema Master student PhD student at TU Delft
3 Ana Stravs Master student PhD student at Institute of Molecular Biotechnology, Vienna
4 Enzo Nio Master student PhD student at Klinik für Neurologie Universitätsklinikum Essen
5 Irina Scheer Master student PhD student at University of Fribourg
6 Amy Hassett Master student PhD student at UCD School of Medicine
7 Saffira Tjon Master student PhD student at Okinawa Institute Of Science and Technology
8 Yawende Landbrug Master student Application Specialist at Artinis Medical Systems

Vacancies

There are currently no vacancies on our lab.