Linda Koene

contact

  • l.koene@erasmusmc.nl
  • +31 010 70 37739
  • Room: Ee-1437
  • Dr. Molewaterplein 40, Faculty Building, Rotterdam, The Netherlands

Linda Koene (L.M.C.)

Publications

1. RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity.

Proietti Onori M, Koene LMC, Schäfer CB, Nellist M, de Brito van Velze M, Gao Z, Elgersma Y, van Woerden GM
in PLoS biology 2021
DOI: 10.1371/journal.pbio.3001279

2. Effects of antiepileptic drugs in a new TSC/mTOR-dependent epilepsy mouse model.

Koene LMC, van Grondelle SE, Proietti Onori M, Wallaard I, Kooijman NHRM, van Oort A, Schreiber J, Elgersma Y
in Annals of clinical and translational neurology 2019
DOI: 10.1002/acn3.50829

3. Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome.

Avagliano Trezza R, Sonzogni M, Bossuyt SNV, Zampeta FI, Punt AM, van den Berg M, Rotaru DC, Koene LMC, Munshi ST, Stedehouder J, Kros JM, Williams M, Heussler H, de Vrij FMS, Mientjes EJ, van Woerden GM, Kushner SA, Distel B, Elgersma Y
in Nature neuroscience 2019
DOI: 10.1038/s41593-019-0425-0

4. Motor Learning Requires Purkinje Cell Synaptic Potentiation through Activation of AMPA-Receptor Subunit GluA3.

Gutierrez-Castellanos N, Da Silva-Matos CM, Zhou K, Canto CB, Renner MC, Koene LMC, Ozyildirim O, Sprengel R, Kessels HW, De Zeeuw CI
in Neuron 2017
DOI: 10.1016/j.neuron.2016.11.046
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